Trapped Neutrophil Syndrome in a Border Collie Confirmed Trapped Neutrophil Syndrome in a Border Collie Puppy in Israel

ABST RACT The case report describes a Border collie puppy diagnosed with trapped neutrophil syndrome (TNS), an autosomal recessive inherited neutropenia. The report describes the clinical presentation, the course of the disease and diagnosis. Chronologically it appeared that that vaccination may have been a potential initiating factor in instigating the TNS in the puppy. The puppy also developed clinical signs of hypertrophic osteodystrophy (HOD). It was not possible to determine whether either vaccination and/or the development of HOD were coincidental. To the best knowledge of the author this is the first genetically confirmed case of TNS described in Israel and the first case documented outside the U.K or Australia. It is recommended that TNS should be weighed as a possibility in any Border collie puppy which presents with symptoms of a vague illness and confirmed neutropenia.